Valid Heterogeneous Clinical Trials
Overview
The aim of this project is to validate psychotherapeutic models and assess their effectiveness while maintaining a flexible delivery approach adapted to each unique individual and circumstance without compromising statistical validity.
Research Question
Do the modality delivery variables (time, interventions, and psychological measures) form a stable structure and thus a significant eigenvalue where the use of any technique within an intervention predicts the same eigenvalue indicative of an underlying pattern structure of the psychotherapeutic modality.
Euismod gravida
Example Dataset
This dataset comprises 992 point-in-time records of self-reported happiness and depression in 295 participants, each assigned to one of four intervention technique groups within positive psychology. Each point-in-time measurement consists of a participant’s responses to the 24 items of the Authentic Happiness Inventory and to the 20 items of the Center for Epidemiological Studies Depression (CES-D) scale. Measurements were sought at the time of each participant’s enrolment in the study (pre-test) and after the intervention (post-test).
The data was reformatted to provide a clean dataset for PCA. The pre-test and post-test results are extracted into two columns each for every item. The four intervention groups were kept as categorical variables for between-group comparison.
J. Woodworth, Rosalind; O'Brien-Malone, Angela; Diamond, Mark R.; Schüz, Benjamin (2018). A randomized placebo-controlled trial of positive psychology interventions in Australia. figshare. Dataset. https://doi.org/10.6084/m9.figshare.1577563.v1
Outline
Analysis Methodology
Log & Robust Scaling
Preliminary Analysis
Principal Component Analysis
Clustering
t-SNE
Eigenmode
Results
The aim of this project is to validate psychotherapeutic models and assess their effectiveness while maintaining a flexible delivery approach adapted to each unique individual and circumstance without compromising statistical validity.
The aim of this project is to validate psychotherapeutic models and assess their effectiveness while maintaining a flexible delivery approach adapted to each unique individual and circumstance without compromising statistical validity.
Future Considerations
This dataset comprises 992 point-in-time records of self-reported happiness and depression in 295 participants, each assigned to one of four intervention technique groups within positive psychology. Each point-in-time measurement consists of a participant’s responses to the 24 items of the Authentic Happiness Inventory and to the 20 items of the Center for Epidemiological Studies Depression (CES-D) scale. Measurements were sought at the time of each participant’s enrolment in the study (pre-test) and after the intervention (post-test).